Avocado-soybean unsaponifiables (ASU) are a natural plant extract with direct canine evidence of cartilage protection, inflammation reduction, and subchondral bone preservation. ASU's phytosterols also support gut barrier integrity through the gut-joint axis. Bonza includes ASU in Bounce Bioactive Bites alongside glucosamine, chondroitin, and anti-inflammatory botanicals for multi-pathway joint support.
The science is clear: ingredient elimination alone is not enough. Research consistently shows that dogs with atopic dermatitis have significantly depleted gut bacteria and lower levels of the protective short-chain fatty acids that maintain skin barrier integrity. This guide examines the peer-reviewed evidence behind the gut-skin axis and provides a practical framework for choosing a hypoallergenic diet that addresses both the triggers and the underlying gut dysfunction most guides ignore.
Antibiotics save lives — but research shows they also inflict significant damage on your dog's gut microbiome, depleting beneficial bacteria and impairing recovery for weeks or even months. This evidence-based guide explains what commonly prescribed antibiotics do to the canine gut, how long recovery really takes, and the nutritional strategies proven to support microbiome rebuilding from day one.
GALT — gut-associated lymphoid tissue — is the largest immune organ in your dog's body, housing around 70% of their entire immune system within the intestinal wall. This network of Peyer's patches, M cells, and immune populations continuously monitors everything your dog swallows, deciding what to tolerate and what to fight. When GALT is disrupted, the consequences extend far beyond the gut — driving skin conditions, joint problems, and systemic immune dysfunction. Discover how GALT works and how targeted nutrition can support it.
Canine anxiety affects up to 70% of dogs with behavioural disorders and is a leading cause of shelter relinquishment. Emerging research into the gut-brain axis reveals that specific psychobiotic strains can help reduce anxious behaviours by modulating neurotransmitter production, regulating cortisol levels, and supporting vagal nerve communication between the gut and brain.
This evidence-based guide explains how to select the right probiotic strains for your dog's specific health needs. It covers the science behind how probiotics work — including eight mechanisms of action and their connections to immunity, skin, brain, and other organs through gut-organ axes.
